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Peripheral Blood Smear (PBS)

General · Blood

Available at 0 labs

No lab currently offers this test.

About this test

What is Peripheral Blood Smear (PBS)?

Peripheral Blood Smear is a microscopic examination of a thin layer of blood spread on a slide. It allows a laboratory technician to see the size, shape, and color of blood cells and to look for abnormal cells.

Key Parameters

ParameterWhat it shows
Red blood cell (RBC) morphologyAnemia types, iron deficiency, hemolysis
White blood cell (WBC) count & differentialInfections, leukemias, immune disorders
Platelet appearanceThrombocytopenia, platelet disorders
Presence of abnormal cellsMalignancies, parasitic infections

Why is it done?

  • Routine check‑up or part of a complete blood count (CBC) panel.
  • Evaluation of unexplained fever, fatigue, bruising, or infections.
  • Monitoring patients on chemotherapy or with known blood disorders.

Early Detection

It can help identify signs of anemia, infections, leukemia, or parasitic infections, but it does not diagnose a disease on its own. A doctor interprets the smear along with symptoms, history, and other tests.

What abnormal results may mean

  • Low RBC count or abnormal shape may indicate iron deficiency, vitamin B12 deficiency, or hemolytic anemia.
  • High WBC count or abnormal WBC morphology may suggest infection, inflammation, or leukemia.
  • Abnormal platelets can point to bleeding disorders or bone marrow problems.

Many factors—hydration, recent meals, medications—can affect the appearance of cells.

Who should consider this test?

  • Anyone with unexplained anemia, fever, or bleeding.
  • Patients undergoing chemotherapy or on immunosuppressive therapy.
  • Individuals with a family history of blood disorders.

In short: PBS is a quick, low‑cost way to spot red‑flag changes in blood cells that may need further investigation.

Used for detecting / monitoring

AnemiaLeukemiaLymphomaMultiple MyelomaThalassemiaSickle Cell DiseaseMalaria

Before your test

  • Fasting: No fasting required for PBS.
  • If combined with fasting tests: Follow the longest fasting period required by any test in the panel.
  • Procedure: A small vein (usually in the arm) is cleaned, a needle inserted, and a few drops of blood are drawn. The blood is then spread thinly on a slide and stained.
  • Time: The whole process takes about 5–10 minutes.
  • Comfort: A brief needle prick; most people feel only a quick pinch.
  • Precautions: Stay hydrated, avoid alcohol or strenuous exercise 24 h before if you are also doing other tests that require it.
  • Note: Confirm any specific preparation with your doctor or the lab. This information is educational and not a substitute for professional medical advice.

Sample type: Blood

Report parameter guide

RBC count

Number of red blood cells per unit volume of blood

Low: Can indicate anemia, blood loss, or nutritional deficiencies

High: Can indicate dehydration, polycythemia, or high red cell production

WBC count

Number of white blood cells per unit volume of blood

Low: Can indicate immunosuppression, bone marrow suppression, or severe infection

High: Can indicate infection, inflammation, leukemia, or stress response

Platelet count

Number of platelets per unit volume of blood

Low: Can indicate thrombocytopenia, bone marrow disorders, or increased platelet destruction

High: Can indicate thrombocytosis, inflammation, iron deficiency, or bone marrow stimulation

Frequently asked questions

It examines the size, shape, and color of red and white blood cells and platelets to look for anemia, infections, leukemia, and other blood disorders.